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WE ARE LICHEN METABOLITES
Nature-Inspired Technology
Lichens, a unique symbiosis between fungi and algae, are among highly resilient and versatile organisms. Thriving in extreme climates on rocks and trees, lichens have developed effective defense mechanisms. These bioactive compounds not only protect lichens themselves but also offer notable benefits for human health and cosmetics.
Nature-A Legacy of Traditional Medicine
For centuries, lichens have been revered for their ability to treat wounds, infections, and skin disorders. Across various cultures, these unique organisms have been celebrated for their therapeutic virtues. Modern science confirms their effectiveness, particularly in combating harmful microorganisms such as yeasts and bacteria through advanced mechanisms like protein synthesis inhibition and cell membrane alteration.
Key Advantages for Cosmetics:
– COSMOS-Certified Natural Preservatives: A groundbreaking alternative to chemical preservatives like phenoxyethanol, offering high safety and efficacy.
– Skin Microbiome Friendly: Supports the natural balance of even the most sensitive skin types.
– Sustainable Innovation: Derived from environmentally responsible cultivation in Canada, lichens align with ethical and ecological values.
Why Replace Phenoxyethanol with Lichen-Based Preservatives?
Enhanced Safety
Phenoxyethanol has raised concerns for its potential irritants. Lichen-based solutions are hypoallergenic and gentle on the skin.
Proven Performance
Protects against bacteria, yeast, and mold while extending product shelf life.
Regulatory Compliance
COSMOS-certified preservatives meet the highest standards for natural and organic cosmetics.
CosmosPreserve
Lichens extracted w/ Triethylcitrate
INCI name & Category
TriethylCitrate, Cladonia rangiferina, Cladonia stellaris
Description
CosmoPreserve is a natural multi-functional active ingredient with broad spectrum anti-microbial, anti-oxidant, anti-inflammatory, and cytoprotective properties. The functional activities stem from Lichen metabolites extracted and standardized from Cladonia stellaris and Cladonia rangiferina. Cosmopreserve is COSMOS compliant. Recommended usage level 1%.
Scientific Performance
Laboratory Results
01
Tables and figures – list of metabolites
02
Atranorin – Scientific publications
- Atranorin inhibits NLRP3 inflammasome activation by targeting ASC and protects NLRP3 inflammasome-driven diseases open_in_new
- Anti-inflammatory and toxicity studies of atranorin extracted from Cladina kalbii Ahti in rodents open_in_new
- Redox properties and cytoprotective actions of atranorin, a lichen secondary metabolite open_in_new
- Evaluation of wound healing activity of atranorin, a lichen secondary metabolite, on rodents open_in_new
- In Vitro and in Silico Studies of Lichen Compounds Atranorin and Salazinic Acid open_in_new
- Antioxidant Activity and Mechanisms of Action of Natural Compounds Isolated from Lichens: A Systematic Review open_in_new
- Chemistry Biodiversity – 2023 – In Vitro and in Silico Studies of Lichen Compounds Atranorin and Salazinic Acid open_in_new
- Biochemical Properties of Atranorin-Induced Behavioral and Systematic Changes of Laboratory Rats open_in_new
- Atranorin, a Secondary Metabolite of Lichens, Exhibited Anxiolytic Antidepressant Activity in Wistar Rats open_in_new
- Atranorin is a novel potential candidate drug for treating myelodysplastic syndrome open_in_new
- Atranorin inhibits Zika virus infection in human glioblastoma cell line SNB-19 via targeting Zika virus envelope protein open_in_new
- Atranorin an antimicrobial metabolite from lichen Parmotrema rampoddense exhibited in vitro anti-breast cancer activity through interaction with Akt open_in_new
- Antinociceptive Activity of Atranorin in Mice Orofacial Nociception Tests open_in_new
- The Comprehensive Roles of ATRANORIN, A Secondary Metabolite from the Antarctic Lichen Stereocaulon caespitosum, in HCC Tumorigenesis open_in_new
- The antimicrobial activity of extracts of the lichen Cladonia foliacea and its (-)-usnic acid, atranorin, and fumarprotocetraric acid constituents open_in_new
- Pleiotropic Potential of Evernia prunastri Extracts and Their Main Compounds Evernic Acid and Atranorin- In Vitro and In Silico Studies open_in_new
- Murine breast carcinoma 4T1 cells are more sensitive to atranorin than normal epithelial NMuMG cells in vitro- Anticancer and hepatoprotective effects of atranorin in vivo open_in_new
- Cytotoxic, apoptotic and cell migration inhibitory effects of atranorin on SPC212 mesothelioma cells open_in_new
- Clastogenic-effect-of-atranorin-evernic-acid-and-usnic-acid-on-human-lymphocytes open_in_new
- Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid. open_in_new
- Usnic acid and atranorin exert selective cytostatic and anti-invasive effects on human prostate and melanoma cancer cells open_in_new
- Therapeutic Effects of Atranorin towards the Proliferation of Babesia and Theileria Parasites open_in_new
- The lichen secondary metabolite atranorin suppresses lung cancer cell motility and tumorigenesi open_in_new
03
Usnic Acid – Scientific Publications
- The antimicrobial activity of extracts of the lichen Cladonia foliacea and its (-)-usnic acid, atranorin, and fumarprotocetraric acid constituents. open_in_new
- Usnic acid alleviates inflammatory responses and induces apoptotic open_in_new
- Usnic acid attenuates 7 12‐dimethylbenz a anthracene DMBA induced oral open_in_new
- Enantioselective activity of usnic acid – a comprehensive review and futureperspectives open_in_new
- Cladonia lichens and their major metabolites as possible natural antioxidant, antimicrobial and anticancer agents open_in_new
- Usnic‐Acid‐Functionalized Silk Fibroin Composite Scaffolds for Cutaneous Wounds open_in_new
- Usnic acid suppresses cervical cancer cell proliferation by inhibiting PD‐L1 open_in_new
- Usnic acid as potential inhibitors of BCL2 and P13K protein through network pharmacology-based analysis molecular docking and molecular dynamic simul open_in_new
- Usnic acid as calcium ionophore and mast cells stimulator open_in_new
- Usnic acid alleviates testicular ischemia reperfusion injury in rats by modulating endoplasmic reticulum stress open_in_new
- Usnic acid- from an ancient lichen derivative to promising biological and nanotechnology applications open_in_new
- Usnic acid enantiomers restore cognitive deficits and neurochemical alterations induced by Aβ1-42 in mic open_in_new
- Usnic acid derivatives as tau-aggregation and neuroinflammation inhibitors open_in_new
- Usnic acid attenuates genomic instability in Chinese hamster ovary CHO cells as well as chemical-induced preneoplastic lesions in rat colon open_in_new
Request a Sample
By incorporating Cladonia Stellaris Extract and Cladonia Rangiferina Extract into your formulations, you bring the power of nature to the forefront—providing safe, effective preservation while enhancing skin health.
These innovative ingredients embody the perfect harmony between science, sustainability, and skincare excellence.
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HEAD OFFICE
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St-Laurent, Quebec H4S 1A7
MANUFACTURING
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Pointe-Claire, Quebec H9R 1A8
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Call us: +1(514)333-1432 or Toll-Free: 1(866)929-6765
Head Office
4930 ch. Bois Franc
St-Laurent (QC) Canada
H4S 1A7
Stay in Touch
Sign up for Newsletter
Join the revolution in natural preservatives. Sign up to learn more and discover how these solutions can enhance your cosmetic formulations.
