BioLichen CosmosPreserve™

A patented multifunctional preservative active powered by lichen metabolites

INCI: Triethyl Citrate, Cladonia (rangiferina/ stellaris) Extract
Category: Natural multifunctional active

Overview

BioLichen CosmosPreserve™ is a COSMOS-certified, bio-based multifunctional active that delivers broad-spectrum anti-microbial activity along with antioxidant, anti-inflammation, antifungal and cytoprotective properties. It serves as a modern alternative to conventional preservative systems like phenoxyethanol.

COSMOS certified | Recommended usage level: 1%

WE ARE LICHEN METABOLITES

Nature-Inspired Technology

Lichens are a remarkable symbiosis between fungi and algae, making them some of the most resilient organisms in nature. They thrive on rocks, trees, and in some of the world’s harshest climates by developing powerful natural defense systems. These bioactive compounds protect the lichens themselves and offer multifunctional properties that are highly valued in cosmetics and personal care. Rich in antioxidant, antimicrobial, antifungal, and cytoprotective properties, lichen-derived actives represent a new frontier in bio-based preservation technology.

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Nature-A Legacy of Traditional Medicine

For centuries, lichens have been revered for their ability to treat wounds, infections, and skin disorders. Across various cultures, these unique organisms have been celebrated for their therapeutic virtues. Modern science confirms their effectiveness, particularly in combating harmful microorganisms such as yeasts and bacteria through advanced mechanisms like protein synthesis inhibition and cell membrane alteration.

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WHY CHOOSE BIOLICHEN COSMOSPRESERVE™ 

Why Consider Lichen-Based Preservation as an Alternative to Synthetics like Phenoxyethanol?

Key Advantages for Cosmetics

COSMOS-Certified Natural Preservative: offering a safe and effective alternative to traditional synthetic preservatives such as phenoxyethanol.

Skin Microbiome Friendly: Gentle and compatible with the skin’s natural barrier, respecting its ecosystem and suitable for sensitive skin.

Sustainable Innovation: Derived from environmentally responsible cultivation in Canada, lichens align with ethical and ecological values. Sourced from environmentally friendly harvesting in Canada, in line with sustainable and ethical values of innovation in personal care.

Who It’s For

BioLichen CosmosPreserve™ is built for professionals driving innovation in formulation science:

  • Skincare & Personal care Formulators & R&D Chemists – seeking broad-spectrum, formulation-friendly preservation with added functional benefits
  • Formulation Houses – looking for versatile preservation systems compatible with multiple product formats
  • Skincare & personal care Raw Material Suppliers & Distributors – sourcing multifunctional actives aligned with ECOCERT and COSMOS standards
  • Personal Care Developers – creating performance-driven skincare, personal care, and cosmetic applications
Who It’s For - BioLichen

Our Certifications

ORGANIC CERTIFIED PRESERVATIVES & ACTIVE INGREDIENTS
STUDIES & RESULTS THAT SUPPORT CLAIMS

Published Scientific References

02

Atranorin – Scientific publications

03

Usnic Acid – Scientific Publications

Frequently Asked Questions (FAQ)

BioLichen CosmosPreserve™ is a 100% natural multifunctional composition designed to replace traditional/synthetic preservatives in personal care formulations.

It is a blend of: TriethylCitrate, Cladonia stellaris (lichen) extract, and Cladonia rangiferina (lichen) extract. These lichens contain active compounds (lichen metabolites) like Usnic acid isomers, Atranorin, Fumarprotocetraric acid, and Perlatolic acid.

In BioLichen CosmosPreserve™, triethylcitrate acts as: A carrier and solubilizer for the active lichen metabolites (Usnic acid, Atranorin). A synergist to boost the broad-spectrum antimicrobial activity of the natural actives. Triethyl citrate is an ester of Citric acid and ethyl alcohol.

No. When used at the recommended concentration of 0.75% to 4%, BioLichen CosmosPreserve does not contain any of the 26 known allergens or sensitizers listed in Annex III of the EC Cosmetic Regulation 1223/2009. Therefore, no allergen declaration is required under EU regulations for either leave-on or rinse-off products when used as directed.

No, BioLichen CosmosPreserve™ was not tested on animals.

CosmosPreserve™ is composed of:

Triethyl Citrate, which is sourced naturally from fermented citric acid and ethyl alcohol.

Cladonia Rangiferina and Cladonia Stellaris (lichen biomass), harvested in Canada.

The product is in full compliance with European Cosmetic Regulation 1223/2009.

Usnic acid exists in two enantiomeric forms: (+) and (–). While most published studies focus on the (+) form, CosmosPreserve™ contains the rarer (–) Usnic acid. We are currently conducting targeted research on the antimicrobial and preservative activity of (–) Usnic acid, which may demonstrate a distinct efficacy and safety profile.

Antimicrobial (broad-spectrum). Antioxidant. Anti-inflammatory. Cytoprotective. Supports natural and clean-label formulations. Offers UV screening effects at 235nm, 250nm, and 285nm

At 0.75%, CosmosPreserve™ passes USP preservative efficacy testing. Recommended dosage is 1%

100% natural origin. Multifunctional active: Provides additional skin benefits (anti-inflammatory, antioxidant, etc.). Ideal for natural, organic, and label-friendly cosmetic formulations.

CosmosPreserve is composed of 100% natural, COSMOS-certified ingredients and does not contain known microbiome-disrupting agents such as harsh alcohols, parabens, or broad-spectrum biocides. Its key ingredient, Triethyl Citrate, is a gentle, non-irritating ester that has been used in formulations designed for sensitive skin and is known for its skin-compatibility.

While direct microbiome clinical testing has not yet been completed for CosmosPreserve™ , its mild preservative mechanism, low use concentration, and lack of known microbiome disruptors suggest that it is a good candidate for microbiome-friendly formulations. For brands seeking to make this claim, we recommend conducting 3rd-party in vitro or in vivo microbiome tests on final formulations containing CosmosPreserve™.

Yes. CosmosPreserve™ has been tested across a variety of formulation bases, demonstrating good compatibility and performance. We provide guidance on how to integrate the ingredient efficiently during the formulation process.

Yes. Published scientific literature on Atranorin and Usnic acid supports wound-healing potential through anti-inflammatory and antioxidant actions, promoting skin regeneration.

Antioxidant activity (confirmed by studies on lichen metabolites). Anti-inflammatory activity (through inhibition of NF-κB and inflammasome pathways). Cytoprotective and UV-screening properties. These support positioning CosmosPreserve™ as a multifunctional active, avoiding regulatory restrictions associated with standalone preservatives in Europe.

Emulsions, Surfactant-based systems. Hot or cold processed formulations.

CosmosPreserve is a liposoluble preservative. For optimal efficacy, it should ideally be added to the lipid phase or the surfactant system of your formulation.

It is heat-stable and can be incorporated into the heated phase (40–60 °C), either in the melted lipid phase or during the hot emulsion phase. Alternatively, CosmosPreserve™ may also be added at room temperature during the final formulation stage, however, ensure proper dispersion throughout the formula.

Recommended dosage at 1%. For value-added benefits, 1-4% dosage is recommended depending on formula.

Appearance: Transparent yellow liquid. Thermostable and liposoluble. Easily integrates into emulsions and surfactants.

CosmosPreserve™ is standardized for two primary bioactive compounds: Usnic acid and Atranorin, known for their antimicrobial properties. Additionally, the extract contains other lichen-derived metabolites in smaller concentrations, including Fumarprotocetraric acid, which may contribute to its overall preservative activity.

Yes. We offer process and integration guidelines to ensure CosmosPreserve™ is effectively stabilized and functional in your final formula. Reach out to receive tailored support based on your formulation type.

CosmosPreserve™ is COSMOS Certified. It is 100% natural ingredient suitable for organic and natural formulations.

Yes. CosmosPreserve™ is a blend composed of Triethyl Citrate, Cladonia Rangiferina, and Cladonia Stellaris. The raw materials are 100% of vegetable origin.

Triethyl Citrate is made via esterification of ethanol (from sugar beet fermentation) with citric acid (from cornstarch fermentation).

Lichen biomass is naturally harvested and air-dried.

Based on suppliers’ declarations, CosmosPreserve™ meets Halal and Kosher requirements.

Challenge tests have been performed across multiple formulation bases to evaluate efficacy. Additionally, we are actively studying the effects of pure (-) Usnic acid on select organisms, which differs from commonly studied (+) Usnic acid.

  • SDS (Safety Data Sheet)
  • COA (Certificate of Analysis)

Yes. When used at 0.75–4%, CosmosPreserve™. Does not require allergen labeling under EC Regulation 1223/2009. Complies with preservative efficacy requirements for topical use under USP standards

Pricing depends on volume and engagement terms. Please request a quote.

Yes. CosmosPreserve™ is available in 1kg, 20 kg carboys, 200 kg drums, and 1000 kg totes with tiered pricing.

Additional documentation can be provided upon request.

Cladonia Rangiferina

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By incorporating Cladonia Stellaris Extract and Cladonia Rangiferina Extract into your formulations, you bring the power of nature to the forefront, providing safe, effective preservation while supporting product performance and formulation integrity.

These innovative ingredients embody the perfect harmony between science, sustainability, and formulation excellence.






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    Head Office

    4930 ch. Bois Franc
    St-Laurent (QC) Canada
    H4S 1A7

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